
When a physician observes the signs and symptoms of “major depressive disorder” in someone—the difficulty sleeping and eating, the weight loss, the absence of interest in a world which once pleased her, the feelings of helplessness and hopelessness—he is likely to prescribe anti-depressant drugs. When a patient asks questions about the need for drugs, she (I use the feminine to remind us that more than twice as many women as men are diagnosed with depression) is often told, “Depression is a biochemical disorder like insulin-dependent diabetes. Diabetics need insulin because their pancreas doesn’t work properly. And you need the drugs, the selective serotonin reuptake inhibitors (SSRIs), like Paxil and Prozac, to raise your levels of serotonin.”